It's Not a Royal Business: The History of Hemophilia Without Myths

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Published on Nov 22, 2023
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How scientists have been trying to cure hemophilia for decades, and what do lime, snake venom, and genetic engineering have to do with it? In this episode, we tell you how we have almost defeated the disease of kings and why it is high time to stop calling it that. Expert of the episode: Ekaterina Schiller, hematologist of the highest category, head of the pediatric hematology department at UPD. Dear listeners, in this episode, we made several factual errors. Firstly, the royals did not suffer from hemophilia A, but from hemophilia B. They are indistinguishable to the eye. Secondly, no one has created any cryoprecipitate of factor IX. Before the appearance of an isolated preparation of this factor, whole plasma was transfused for hemophilia B. Thirdly, 300,000 women with hemophilia in the world is an estimated value based on the probability of getting sick. It includes not only hemophilia, but also other coagulopathies, which are more common. In fact, there are less than a dozen diagnosed cases of true hemophilia A or B in women in Russia, and 21 cases in Spain, for example. If we transfer this data to the entire world, it turns out that the total number is a couple of orders of magnitude smaller. Nevertheless, there are still many women with pathological bleeding, they just lack other clotting factors. We apologize and wish you a good listening! Advertising. OOO FLOWWOW. INN 9702020445 A friend and partner of this episode is Flowwow, an international marketplace of local brands. Promo code POCHEMU gives a 15% discount on your first order and is valid until March 31, 2024. https://flowwow.com/s/POCHEMU?erid=2S... Subscribe to bonus episodes of the Either/Or studio in Apple Podcasts https://cutt.ly/poc10epap or in Telegram https://cutt.ly/poc10eptg Host - Fyodor Katasonov Scriptwriter - Ivan Korneev Editor - Semyon Sheshenin Producers - Masha Aglicheva, Lika Kremer and Ksenia Krasilnikova Medical editor - Nigina Begmurodova Sound engineer - Lesha Vorobyov Composer - Kira Weinstein

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