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https://www.medicinaeinformazione.com/ / medicinaeinformazione / einformazione Over a third of people with chronic inflammatory bowel disease, therefore Crohn's disease or ulcerative colitis, may also present symptoms of other immune-mediated diseases, in particular rheumatological diseases, but even those affected by rheumatoid arthritis or spondyloarthritis may present extra-articular symptoms over time, particularly gastrointestinal. From this information emerges the strong need for greater attention at the time of diagnosis and a multidisciplinary rheumatologist-gastroenterologist approach to best manage the therapeutic path of each patient. We discuss this with Prof. Roberto Caporali, Director of Rheumatology at the ASST Gaetano Pini-CTO in Milan and Director of the School of Specialization in Rheumatology at the University of Milan, to whom we asked: The link between inflammatory bowel diseases and rheumatological diseases, the common ground is immune-mediated inflammation? Are they manifestations of the same disease or comorbidity? Have you understood? How many patients who receive a diagnosis of inflammatory bowel disease are also evaluated for the rheumatological picture and vice versa? Is this link sufficiently known? And what are the alarm bells, the so-called red flags? Extra-articular or extra-intestinal symptoms often arise at a later stage, can multidisciplinary management prevent or at least better manage the concomitance of the two pathologies? (less response to diseases when there is concomitance) Multidisciplinary approach but also synergy between specialists to obtain remission of the underlying pathology but also of the other manifestations. Therapeutic innovations for personalized paths to send both manifestations into remission