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A few weeks ago, the authorization for the use of Fostemsavir also for Italian patients for people living with HIV who are heavily pretreated and do not respond to other therapies was granted. We discuss this with Prof. Antonella Castagna, Associate Professor of Infectious Diseases, Vita-Salute San Raffaele University; Head of the Functional Unit of Infectious Diseases Division, Scientific Institute IRCCS San Raffaele.