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Hey, here is the 2nd part of the video on tolerance. In this video we will talk about regulatory T lymphocytes: natural or induced, anergy, antigen sequestration, or apoptosis. If you haven't seen the first video yet, or want to see it again! here is the link: • Tolerance and Autoimmunity Part 1: ... Timestamps: 0:00 intro 0:10 Brief reminder on the development and tolerance of LTs 1:51 Introduction to peripheral tolerance (anergy and regulatory LTs) 2:58 Peripheral tolerance mechanisms, overview 4:43 Ignorance and indifference towards self antigens (antigen sequestration) 6:51 Regulatory LTs 10:24 Let's recap References: 1. Kenneth Murphy, Casey Weaver - Janeway's Immunobiology-Garland Science (2016) 2. (Kindt, Kuby Immunology) Judy Owen, Jenni Punt, Sharon Stranford - Kuby Immunology-WH Freeman (2013) 3. Abul K. Abbas, Andrew HH Lichtman, Shiv Pillai - Cellular and Molecular Immunology-Elsevier (2017)⇒ on some things only