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While the last fifty years have seen a great deal of scientific progress on the question of the appearance of life on Earth, the question still fascinates scientists. What tools do they have at their disposal? Are we really born from stardust? What remains to be discovered? Thomas Georgelin, Surface Reactivity Laboratory (LRS) Marco Saïta, Institute of Mineralogy, Materials Physics and Cosmochemistry Stéphane Tirard, François Viète Center for the History of Science and Technology Frances Westall, Center for Molecular Biophysics in Orléans