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New facts about the tactics of treating coronary heart disease are reflected in the Ischemia study, an important source of evidence-based information. The results of the international randomized study conducted by the AHA have significantly influenced the opinion of experts on how to manage a patient with chronic coronary heart disease and have shown that patients with stable coronary heart disease should be more carefully selected for invasive treatment, taking into account the severity of angina and the possibility of antianginal therapy. Prof. Gilyarevsky Sergey Rudzherovich answers in detail the question: what should be the tactics of treating coronary heart disease today, including in patients who have quite pronounced myocardial ischemia? The Nexus platform presents evidence-based facts that change the understanding of the approach to treating patients with coronary heart disease. Gilyarevsky Sergey Rudzherovich - MD, Professor, Department of Clinical Pharmacology and Therapy, Russian Medical Academy of Continuous Professional Education of the Ministry of Health of the Russian Federation, Moscow 0:00 Introduction 0:45 Analysis of initial invasive tactics (ISCHEMIA Study) 10:00 Vasospastic angina 19:36 TRADE-OFF Compromises, approaches and options for drug therapy of coronary heart disease 31:30 Conclusion