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Today we will talk in detail about systemic scleroderma. Together with a rheumatologist, we will delve deeper into understanding this disease: what are its symptoms, how to treat it, and how it affects the quality of life. We prepared the questions for this video together with patients who suffer from SSc, and Lidiya Petrovna Ananyeva, MD, professor, and leading researcher at the V.A. Nasonova Research Institute of Rheumatology, answers them. Rheumofactor is an educational and informational channel for everyone who has encountered autoimmune rheumatic diseases. Competent doctors and experts from patient organizations answer the most important questions for patients. How do genetically engineered biopreparations work? Can you skip taking medications? How to relieve pain? We discuss these and many other topics that will help you study your disease, learn to control it, and maintain your quality of life.