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Bashar al-Assad's opponents are advancing towards Hama and Homs, two other big cities of Syria, after capturing Aleppo. There is also a possibility of capturing these two cities. If Assad is overthrown, the pillar of the anti-Israel policies of the Islamic Republic in the region and what the Islamic Republic calls the axis of resistance will collapse. The possible fall of Assad can be a big and irreparable blow to the Islamic Republic and the government of Ali Khamenei.