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In the United States, the abuse of opioid drugs has led to a real epidemic. How are things in Italy? To avoid the abuse in the use of these drugs, what has been done in our country and what still needs to be done? We talked about it with Professor Silvia Natoli, whom we met in Riva del Garda on the occasion of the XXII National Congress of the Cultural Area Pain and Palliative Care (ACD) organized by the Italian Society of Anesthesia Analgesia, Resuscitation and Intensive Care (SIAARTI).