□ Broadcast date and time: Friday, November 17, 2023 at 10:20 PM □ PD in charge: Ji Seong-yoon, Han Taek-won □ Writer in charge: Kim Bae-jung, Kim Hyeon-jung □ Cast: Shin Hye-won (Neurologist at Chung-Ang University Hospital) □ Broadcast channel IPTV - GENIE TV 159 / BTV 243 / LG U+ 145 Skylife 90 Cable - DLive 138 / Hyundai HCN 341 / LG Hellovision 137 / BTV Cable 152 The text below may differ from the actual broadcast content. Please check the broadcast for more accurate information. ▶ Definition of Parkinson's disease ▶ Symptoms of Parkinson's disease ▶ Differences from Alzheimer's disease ▶ Symptoms by stage ▶ Importance of early diagnosis ▶ Methods of diagnosing Parkinson's disease ▶ Development of treatments ▶ Limitations of drug treatment ▶ Deep brain stimulation ▶ Development of auxiliary treatments ▶ Exercise therapy ▶ Digital healthcare ▶ Medical AI Q&A ◆ Neurologist Shin Hye-won (hereinafter referred to as Shin Hye-won): Hello. I am neurologist Shin Hye-won. The topic I will be teaching today is understanding and treating Parkinson's disease. ◇ Voice actor Park Sang-hoon: Parkinson's disease is called a representative degenerative brain disease along with dementia. As our society enters a super-aging society, the number of people visiting hospitals due to Parkinson's disease is also increasing. About 1.5% of the entire population over 60 years of age suffers from Parkinson's disease. What are the causes and treatments of Parkinson's disease, which is called another enemy of the aging society? (Definition of Parkinson's disease) ◆ Shin Hye-won: What do you know about Parkinson's disease? If you walk with a stooped posture, drag your legs, have tremors in your hands and feet, stiff joints, a small voice, and no facial expressions, you may suspect that you have Parkinson's disease. Parkinson's disease was first reported in 1817 by Dr. James Parkinson in his essay Tremors and Paralysis, in which he reported patients with symptoms such as hand tremors, stiffness, gait abnormalities, and stooped postures. At the time, only symptoms were reported, so it was naturally impossible to know why this disease occurred. Parkinson's disease is a disease in which toxic protein aggregates called Lewy bodies accumulate in the substantia nigra, an area in the midbrain where dopamine neurons are located, and as a result, dopamine neurons disappear and do not function normally, causing symptoms. So what is dopamine, and what symptoms occur when dopamine cells disappear? Dopamine is one of the many neurotransmitters in the brain. Recently, interest in dopamine has been increasing due to social issues such as game addiction and drug addiction. Dopamine, which is related to pleasure and addiction, is dopamine that acts on the nervous system called the limbic system. The dopamine neurons of the midbrain substantia nigra that are lost in Parkinson's disease are connected to the motor center. They function to enable the body to move smoothly. Therefore, the role of the dopamine cells that are lost in Parkinson's disease is that they are cells responsible for motor functions, so when dopamine cells are lost in Parkinson's disease, the body's movements become slow and smooth movement becomes difficult. (Symptoms of Parkinson's disease) ◆ Shin Hye-won: Then, what does this difficulty in smooth movement mean? Let's take a closer look at the various motor symptoms of Parkinson's disease. First, bradykinesia, which is a reduced range of movement or slow speed, is the most representative symptom. And when sitting comfortably or lying down, parts of the body such as the hands, legs, and jaw may tremble in a relaxed position with muscles. This is called resting tremor and is a characteristic symptom of Parkinson's disease. And stiffness in the joints may appear. In addition, the stride is narrow... (omitted) PD Han Taek-won ([email protected]) ▶ Original article: https://www.ytn.co.kr/_ln/0103_202311... ▶ Report: https://mj.ytn.co.kr/mj/mj_write.php ▣ Subscribe to YTN YouTube channel: http://goo.gl/Ytb5SZ ⓒ YTN Unauthorized reproduction, redistribution, and use of AI data are prohibited