Lung cancer is not only one of the most common, but also one of the deadliest forms of cancer. But a lot is happening in treatment: molecular diagnostics, immunotherapy and soon perhaps even a new screening? The expert Dr. Sylvia Gütz brings order to the complex diagnostics and treatment of lung cancer. Together with the chief physician and pulmonologist at St. Elisabeth Hospital in Leipzig, we use a case study to trace the path from the initial diagnosis to the tumor board. Table of contents: 00:00:00 Intro 00:02:17 The basics: small cell vs. non-small cell 00:05:31 Aetiology of the various entities 00:07:38 Epidemiology 00:10:54 Clinical picture: How is lung cancer recognized? 00:13:54 Special form of Pancoast tumor 00:16:39 Does screening make sense? 00:25:11 Case study: Initial diagnosis in the practice 00:32:03 Radiological and molecular diagnostics in the clinic 00:36:51 Classification according to TNM and UICC 00:42:01 Molecular diagnostics and driver mutations 00:47:26 Supplementary diagnostics: Lung function, cardiac echo, etc. 00:48:51 The role of immunochemotherapy 00:54:55 Tumor board 00:56:55 Inoperable tumor, what now? 00:57:55 Case study: Choice of therapy and course 01:01:53 Clinical studies in tumor therapy 01:03:19 Take-home messages 01:05:49 Outlook *More information on lung cancer in AMBOSS:* https://go.amboss.com/lungenca *For the podcast episode “COPD: From initial diagnosis to palliation”:* https://go.amboss.com/63z *For the podcast episode “Tobacco addiction: Address it correctly, save lives”:* https://go.amboss.com/iyv *Direct to the TNM classification of lung cancer in AMBOSS:* https://go.amboss.com/rv2 *Direct to the UICC classification of lung cancer in AMBOSS:* https://go.amboss.com/ql1 *Information on clinical studies by the German Cancer Society:* https://go.amboss.com/zee *More about the AMBOSS podcast:* https://go.amboss.com/podcast *Disclaimer:* The contents of the AMBOSS podcast are purely academic. They are for information, learning and training purposes only and are intended for medical staff, medical students and other people working in the healthcare sector. The content is not suitable for treating real cases and is not a substitute for a visit to the doctor. The podcast is created with the greatest possible care. However, AMBOSS GmbH does not guarantee the accuracy, completeness and timeliness of the content. Statements made by interviewees are the sole responsibility of those interviewed - they do not reflect our point of view. We select our interviewees solely on the basis of their scientific expertise. We will separately indicate any economic connections our guests have to supporters of our podcast that we are aware of.