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Longevity is not the record of how many years you accumulate, but how many years you live well. How is it possible to do this according to science? Filippo Ongaro, a surgeon, specialized in sports medicine, introduces us to the topic. He was the astronauts' doctor from 2000 to 2007. The first Italian to be certified in functional medicine and antiaging in the USA at the American Board of Regenerative and Antiaging Medicine (ABAARM), he founded and directed the first antiaging medicine center in Italy. The conference was held in Peccioli in October 2024, on the occasion of the second edition of the Symposium on Change.