Liver cirrhosis – a threat to life? Gastroenterologist Vladimir Loginov tells us

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Федеральная сеть клиник Евроонко

Published on Oct 15, 2020
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Liver cirrhosis is a consequence of hepatitis of any etiology. In this process, normal liver cells - hepatocytes - die. The area of ​​necrosis (cell death) is replaced by connective tissue, which forms nodes of various sizes. Changes in the normal structure of the liver lead to persistent disruption of its functions, the main one of which is the purification of blood coming through the venous vessels. Cirrhosis also disrupts the organ's ability to self-regenerate. With cirrhotic damage, the liver hardens, which leads to portal hypertension - increased pressure in the portal vein system. At the same time, blood flow to the spleen and veins of the stomach vault, as well as to the veins of the esophagus increases, which ultimately leads to their varicose veins. Bleeding from varicose veins of the esophagus is a serious complication of cirrhosis and one of the main causes of death. Currently, there are several endoscopic methods for stopping bleeding. First of all, the treatment tactics should be aimed at preventing cirrhosis and eliminating the existing causative factors. The main ones are alcohol consumption, viral hepatitis B and C, as well as the toxic effects of some drugs. Previously, viral hepatitis required long-term therapy with a large number of side effects. Now the use of direct-acting antiviral drugs allows us to effectively treat both infectious diseases. Hepatitis of any etiology can cause not only cirrhosis, but also malignant neoplasms of the liver. Compensated forms of cirrhosis can be latent or with unclear symptoms. Hepatitis and cirrhotic liver damage can be detected with the help of an elementary examination - contacting a specialist and taking laboratory tests. The prognosis for patients with cirrhosis depends on the stage of the disease. With compensated forms and timely treatment, it is favorable, with decompensation of the disease, there is a high mortality rate. In case of liver cirrhosis, a liver transplant can be a way out of the situation. Unfortunately, it is rarely carried out due to legal aspects and a shortage of donor organs. 0:00 – Introduction 0:53 – What is liver cirrhosis 2:56 – Portal hypertension and esophageal varices 4:48 – Alcohol and hepatitis B, C as the main cause of liver cirrhosis 8:15 – About diagnostics 10:30 – Methods of treating liver cirrhosis 12:13 – Prognosis for cirrhosis and liver transplantation Join our groups on social networks: VKontakte: https://vk.com/euroonco Odnoklassniki: https://ok.ru/group/62667235590309 Telegram: https://t.me/euroonco_ru ▲ We publish new materials on the treatment, diagnosis and prevention of oncological diseases. ▻ Contact us to make an appointment with an oncologist: 8 (800) 511-37-69

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