My blog for further reading ⏩ https://bit.ly/Insulin_Blog As a medicine, insulin is of central therapeutic importance for many diabetics. In these patients, the pancreas cannot produce insulin, which is the case with type 1, or the insulin "loses" its effect, which is the case with type 2. Therefore, depending on the type of diabetes and the stage of the disease, they have to take in the hormone from outside. Frequency of diabetes mellitus: - AIDS of the 21st century - 4 million men and women in Germany - In 2045, 8-10% of all people in industrialized countries will develop diabetes - 90% type 2, 5% type 1 - 70% of children whose parents both have type 2 will also develop this diabetes Insulin as a hormone Insulin is a hormone, a so-called peptide hormone. Chemically speaking, it consists of individual amino acids that are linked together - like a string of pearls. This is then called a peptide chain. In the case of insulin, we are dealing with two peptide chains: the so-called "A chain" with 21 amino acids and the "B chain" with 30 amino acids. These two chains are linked to one another. Insulin itself functions as a hormone in our body and influences various vital metabolic processes in our body. Functions of insulin: - increases the absorption of amino acids and glucose into the cells of various tissue types - inhibits gluconeogenesis in the liver and thereby reduces the amount of new glucose formed in the body - promotes the oxidative breakdown of glucose - increases the buildup of glycogen as an intermediate storage facility for glucose and prevents glycogen breakdown - stimulates the formation of fat from glucose Insulin as a drug Insulin is used as a drug when the body is no longer able to lower blood sugar or is not able to lower it sufficiently. This is the case in three different areas of application: 1. Diabetes mellitus, type 1 2. Advanced diabetes mellitus, type 2 3. after a pancreatectomy, i.e. surgical removal of the pancreas. As always, the same applies to insulin: no effect without side effects. Typical side effects are, of course, hypoglycemia and weight gain, as insulin, due to its anabolic effect, converts sugar from the blood into fat, etc. And this can lead to weight gain. Allergic reactions and so-called lipodystrophy. This leads to an increase in subcutaneous fat, which can lead to poorer absorption of insulin and ultimately to impaired metabolism. Typically occurs when insulin is injected multiple times in the same place. ▬ About this channel ▬▬▬▬▬▬▬▬▬▬▬▬ With “Video Visit Dr. Weigl" you have found the current and medical-scientific channel that describes topics related to pain, #medicine and #health in an understandable way but based on facts, guidelines and studies. In particular, I address common diseases such as diabetes mellitus and also medication such as #insulin. ▬ Even more videos ▬▬▬▬▬▬▬▬▬▬▬▬▬ What is diabetes mellitus?: https://bit.ly/DiabetesMellitus_Video What is diabetic polyneuropathy and what can you do about it?: https://bit.ly/DiabetesFolgen_Video Is Ozempic an alternative to insulin?: https://bit.ly/Ozempic_Video Everything about the diabetes drug Metformin - dosage and side effects: https://bit.ly/Metformin_Video Cholesterol-lowering drugs such as Simvastatin & Atorvastatin - effects, dosage & side effects: https://bit.ly/Cholesterinsenker_Video ▬ Recommended literature ▬▬▬▬▬▬▬▬▬▬▬▬ Metformin - the oral antidiabetic drug: https://bit.ly/Metformin_Blog Gout - causes, symptoms & therapy: https://bit.ly/Gicht_Blog Simvastatin - cholesterol reduction and cardioprotection: https://bit.ly/Simvastatin_Blog What is diabetes insipidus? Increased urine excretion but why?: https://bit.ly/DiabetesInsipidus_Blog Ozempic - the new miracle weapon for losing weight and diabetes?: https://bit.ly/Ozempic_Blog ▬ Social Media ▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬ ►Facebook: https://bit.ly/facebook_DrWeigl ►Website: https://doktorweigl.de ►Twitter: https://bit.ly/Twitter_DrWeigl ►Instagram: / doktorweigl ▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬ Legal notice / disclaimer: The videos are for your information only and never replace personal advice, examination or diagnosis by a licensed, qualified specialist. In particular, when taking medication, you should consult your doctor and read the package insert. The content provided cannot and may not be used to make independent diagnoses. Liability excluded. Facebook & Instagram icon: Icon made by freepik from www.flaticon.com Twitter icon: Icon made by Pixel perfect from www.flaticon.com Sound effects obtained from https://www.zapsplat.com