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How does it manifest itself? What treatments are available? Explanations from Professor Anoosha Habibi, a doctor in the red blood cell genetic diseases unit, in the internal medicine department of the Henri Mondor University Hospital in Créteil, in the Paris region, and head of the university diploma "Major sickle cell syndrome" at the University of Paris-Est Créteil. Sickle cell disease, which affects the hemoglobin of red blood cells, is the most common genetic disease. It manifests itself in particular by anemia, characterized by a lack of red blood cells. Sickle cell disease can also cause painful crises and an increased risk of infections. Research is working to develop better treatments to increase the life expectancy of affected patients. Subscribe to find all RFI videos: / @rfi_fr