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Gout is a disease caused by the accumulation of uric acid in the joints. This accumulation can depend on various factors, such as pathologies that cause an overproduction of purines or a reduced ability of the kidneys to eliminate them, but also from the excessive consumption of foods rich in purines, such as shellfish, red meat or beer. But what are purines, and what treatments exist for gout? Augusta Ortolan, of the UOC of Rheumatology of the Fondazione Policlinico Universitario Agostino Gemelli in Rome, tells us.