Metabolic acid-base balance (AAB) in the body is important for the normal functioning of all human systems. Laboratory monitoring of AAB is becoming an important component of emergency care for a patient in the intensive care unit. Speaker: Sergey Georgievich Parvanyan, PhD, Head of the Anesthesiology and Resuscitation Department No. 3 of the All-Russian Center for Emergency and Radiation Medicine named after A.M. Nikiforov, EMERCOM of Russia The webinar will be of interest to anesthesiologists - resuscitators, KLD doctors, clinical residents and students of medical institutes. The webinar covered: 0:28 Determination of acid-base balance 1:24 pH of the environment and interpretation of pH 3:02 Maintenance of acid-base homeostasis 4:25 Buffer systems 5:10 Bicarbonate buffer 5:22 Point of care acid-base balance 5:46 Bicarbonate buffer is 8:05 Reserve of bicarbonate ion 8:48 Restoration of bicarbonate ion capacity 9:41 Kidney damage and acid-base balance 10:30 Speed ​​of response to correction of acid-base balance 10:54 Standard bicarbonate 11:54 Deficiency of buffer systems 13:25 Hemoglobin buffer 13:59 Oxygenated hemoglobin 14:49 When hemoglobin levels decrease 15:03 Acidosis 15:23 Respiratory acidosis/alkalosis 15:36 Metabolic acidosis/alkalosis 16:45 mixed alkalosis/acidosis 16:48 clinical example and result of acidosis study 18:35 second example – metabolic alkalosis 19:56 acid-base balance of a patient on long-term mechanical ventilation 21:29 step-by-step interpretation algorithm 24:04 anion gap 26:11 tissue hypoxia 26:55 cooximetry 28:53 hemoglobin saturation 29:38 carboxyhemoglobin 30:32 smoker's carboxyhemoglobin 31:31 toxic effect of carbon monoxide 31:50 cyanosis and carbon monoxide 34:38 ​​reduced hemoglobin 34:51 carbon monoxide poisoning 35:58 pulse oximeters 37:51 carboxyhemoglobin elimination 38:54 methemoglobin 40:08 sulfhemoglobin 41:52 blood gas analysis 42:05 gold standard for acid-base balance analysis 42:48 arterial blood collection sites 45:00 arterial blood gas exchange parameters 45:51 at what FiO2 were the results obtained? 47:37 Capillary Blood Gas Composition 48:34 Arterialization Technique 49:57 Venous Blood 51:10 Mixed Venous Blood 52:37 Clinical Composition of Venous Blood 53:45 Oxygen Content and Delivery to Tissue 57:00 The Importance of Anemia 1:00:35 Oxygen Supply and Consumption Balance 1:02:15 Oxygen Cycle 1:05:24 Measuring Venous Saturation 1:07:35 Lactate Concentration 1:10:31 Lactate Acidosis 1:17:56 Oxygen Debt 1:26:06 Laboratory and Clinical Monitoring 1:29:42 The Importance of Laboratory Monitoring 1:33:25 Sample Delivery 1:36:24 Regulatory Documents Governing the Placement of the Analyzer Near the Patient 1:45:05 Should Lactate Testing Be Implemented?