Behcet's Disease and Vascular Inflammation - Prof. Dr. Ahmet AKGUL - Prof Dr Ahmet Akgül ahmetakgulTV - World Latest Movie, Series, Videos and Trailers

Behcet's Disease and Vascular Inflammation - Prof. Dr. Ahmet AKGUL

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Published on Mar 18, 2019

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Behçet's disease is a chronic disease. In other words, like all chronic diseases, it lives with us until the end of our lives. Sometimes the complaints increase and sometimes it does not show any symptoms. If you ask why we should be treated or how we should be treated since we have a chronic disease, the aim of the treatment should be to increase our quality of life, to spend time without complaints and diseases despite the existence of the disease. In addition, even if the disease does not end completely, its progression should be stopped and the bad and more serious consequences of the disease in the future should be eliminated. Behçet's disease is a chronic vascular disease that falls into this group. It is an inflammation of the veins, that is, a vasculitis. The disease manifests itself with recurrent mouth and genital area sores, eye inflammation, skin findings and vascular involvement. The summary of the disease is shown in the picture on the side. Behçet's syndrome is among the rare vasculitides, that is, vascular inflammations that can affect all sizes of the vascular and arterial systems in the circulatory system. Although the picture is generally dominated by DVT involvement, which is the vein occlusion responsible for thrombosis, i.e. intravascular coagulation, the problems that arise include a wide spectrum from arterial occlusion, i.e. arterial occlusion, to vascular dilatation, i.e. aneurysm, from superficial thrombophlebitis to superior or inferior vena cava occlusion. In Behçet syndrome with neurological involvement, venous sinus thrombosis, i.e. occlusion, which constitutes one of the two main subgroups of the disease, can be given as an example in terms of vascular involvement, and in this case, a benign clinical picture is usually observed. BEHÇET DISEASE should be considered especially in young patients presenting with signs of increased intracranial pressure. When compared to the frequency of venous involvement in Behçet's disease, arterial involvement, i.e. both inside and outside the brain, is rarely seen and has been reported as 1-5%. However, large arterial involvement carries a high risk in terms of death and morbidity. In young patients diagnosed with stroke, systemic findings of Behçet's disease should definitely be questioned. Behçet's disease is observed more frequently in Middle and Far Eastern societies than in other regional societies. Genetic transmission and family inheritance are important among its causes. Especially the individual's HLA-B5 carrier status is an important factor genetically. The age of onset of Behçet's disease is usually between 20 and 30 years. It affects both women and men with similar frequency.

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