For several years, doctors from the University Clinic have been actively working on the project "Anaplastic Carcinoma: Biotechnology and Therapy", the goal of which was to study the biology of the tumor and create cell models to determine effective treatment regimens for anaplastic thyroid cancer. During the lectures and discussions, conference participants familiarized themselves with the intermediate results of the research at the St. Petersburg University Clinic and were able to ask the most pressing questions to the speakers of the event. Contents 00:00 Introduction 02:32 Molecular basis for malignant transformation of thyrocytes and prospects for the use of tyrosine kinase inhibitors (Anastasia Nikolaevna Vaganova) 23:24 In vivo/in vitro testing of chemotherapy for anaplastic thyroid cancer: opportunities and challenges (Evgeny Viktorovich Kanov) 1:03:20 Morphological aspects of anaplastic thyroid cancer. Immunohistochemical predictors (Vorobyov Sergey Leonidovich) 1:26:03 Comprehensive genomic profiling - a modern trend in the diagnosis of thyroid tumors (Rykov Ivan Vladimirovich) 1:44:50 Modern technologies of molecular imaging of thyroid cancer and development prospects (Rumyantsev Pavel Olegovich) 2:04:40 Modern capabilities of PET-CT in thyroid cancer (Gromova Elena Anatolyevna) 2:24:17 Translational medicine issues regarding the selection of therapy for aggressive forms of non-medullary thyroid cancer (Imyanitov Evgeny Naumovich) 2:52:45 Algorithm for choosing therapy in patients with poorly differentiated non-medullary thyroid cancer. Promising targets for targeted therapy (Dzhelyalov Ernest Serverovich) 3:23:10 Treatment of radioiodine refractory papillary thyroid cancer: standards and current trends (Borodavina Ekaterina Vladimirovna) 4:12:08 Papillary microcarcinoma of the thyroid gland - treatment tactics (Chernikov Roman Anatolyevich) 4:35:27 Anaplastic cancer. Place of surgical treatment (Sleptsov Ilya Valerievich) 4:50:01 Radiation therapy of anaplastic cancer: personal experience and lessons from it (Spiridonova Maria Andreevna, Nikita Andreevich Kataev) 5:10:55 Management of patients with anaplastic carcinoma in clinical practice of KVMT (Timofeeva Natalia Igorevna) 5:24:05 Postoperative management of patients with aggressive forms of non-medullary thyroid cancer. Replacement therapy in the high-risk oncological group (Sleptsov Ilya Valerievich) 5:53:30 New possibilities of antiemetic therapy - real clinical experience (Semenov Leonid Konstantinovich) 6:13:27 Psychological support for cancer patients (Vagaytseva Margarita Valerievna) 6:36:23 Nutritional support for patients with aggressive forms of thyroid cancer (Kulikova Elena Aleksandrovna)