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The development of tumors is caused by genetic damage, which has been clearly proven by research over the last 20 years, and about 800 genes have been identified that cause uncontrolled tumor growth. However, it has long been a puzzle why and how mutations develop? Previously, we thought of these as “random” errors in cell division, but it was incomprehensible why their distribution is so common? For example, in the case of pancreatic cancer, a mutation in a gene called KRAS is present in 80 percent of cases. The same gene is also greatly overrepresented in colon cancer and lung cancer. What causes tumors to develop? Human cells use signals, so-called “signals,” to control the functioning of cells so that their functions are in harmony with each other. If there is a disruption in this communication, an “accident” occurs, which is cancer.